KRT17 Antikörper
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- Target Alle KRT17 Antikörper anzeigen
- KRT17 (Keratin 17 (KRT17))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KRT17 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Produktmerkmale
- Monoclonal Antibody
- Aufreinigung
- Protein A purification
- Immunogen
- Synthetic Peptide
- Klon
- 2K5
- Isotyp
- IgG
- Top Product
- Discover our top product KRT17 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- KRT17 (Keratin 17 (KRT17))
- Andere Bezeichnung
- CK-17 (KRT17 Produkte)
- Synonyme
- K17 antikoerper, Krt1-17 antikoerper, PC antikoerper, PC2 antikoerper, PCHC1 antikoerper, Ka17 antikoerper, KRT17 antikoerper, krt16 antikoerper, si:dkeyp-113d7.7 antikoerper, KRT14 antikoerper, keratin 17 antikoerper, keratin 17 L homeolog antikoerper, keratin 17, type I antikoerper, keratin, type I cytoskeletal 17 antikoerper, Krt17 antikoerper, KRT17 antikoerper, krt17 antikoerper, krt17.L antikoerper, LOC100737113 antikoerper, LOC102177275 antikoerper
- Hintergrund
- May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.
- Molekulargewicht
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Observed_MW: 48 kDa
Calculated_MW: 48 kDa
- UniProt
- Q04695
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