IDE Antikörper
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- Target Alle IDE Antikörper anzeigen
- IDE (Insulin-Degrading Enzyme (IDE))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser IDE Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Produktmerkmale
- Monoclonal Antibody
- Aufreinigung
- Protein A purification
- Immunogen
- Synthetic Peptide
- Klon
- 1H4
- Isotyp
- IgG
- Top Product
- Discover our top product IDE Primärantikörper
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anti-Insulin-Degrading Enzyme (IDE) (AA 491-590) antibody
IDE Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 753-973) antibodyIDE Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 1-250) antibodyIDE Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 920-1019) antibodyIDE Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (N-Term) antibodyIDE Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (Internal Region) antibodyVerified IDE Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 501-800) antibodyIDE Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE Reaktivität: Human WB Wirt: Maus Monoclonal 3H4 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-300, IF 1:100-1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IDE (Insulin-Degrading Enzyme (IDE))
- Andere Bezeichnung
- IDE (IDE Produkte)
- Hintergrund
- This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
- Molekulargewicht
- 118 kDa
- UniProt
- P14735
- Pathways
- SARS-CoV-2 Protein Interaktom
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