XRCC4 Antikörper

Produktnummer ABIN7250143

Produktdetails anti-XRCC4 Antikörper

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRCC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Protein A purification

Immunogen: Synthetic Peptide

Klon: 8K2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu XRCC4

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Andere Bezeichnung: XRCC4 (XRCC4 Produkte)

Synonyme: zgc:73312 antikoerper, MGC81443 antikoerper, homolog of human DNA ligase iv-binding protein XRCC4 antikoerper, 2310057B22Rik antikoerper, AW413319 antikoerper, AW545101 antikoerper, X-ray repair cross complementing 4 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 4 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog antikoerper, DNA ligase IV-binding protein antikoerper, XRCC4 antikoerper, xrcc4 antikoerper, xrcc4.L antikoerper, Xrcc4 antikoerper

Hintergrund: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Molekulargewicht:

Observed_MW: 38 kDa

Calculated_MW: 38 kDa

UniProt: Q13426

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response