beta Catenin Antikörper
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- Target Alle beta Catenin (CATNB) Antikörper anzeigen
- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser beta Catenin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
- Monoclonal Antibody
- Aufreinigung
- Protein A purification
- Immunogen
- Recombinant Protein
- Klon
- 2E4
- Isotyp
- IgG
- Top Product
- Discover our top product CATNB Primärantikörper
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anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Xenopus laevis WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio) WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf, Affe, Hamster, Avian, Cat, Esel, Ziege, Meerschweinchen, Pferd WB, IF Wirt: Ziege Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IF, IHC (p) Wirt: Maus Monoclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C901 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Hamster WB, FACS, IP, ICC Wirt: Maus Monoclonal EM-22 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 4A3H3 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- beta Catenin (CATNB) (Catenin, beta (CATNB))
- Andere Bezeichnung
- Catenin beta (CATNB Produkte)
- Synonyme
- Bfc antikoerper, Catnb antikoerper, Mesc antikoerper, CTNNB antikoerper, MRD19 antikoerper, armadillo antikoerper, ctnnb antikoerper, id:ibd2058 antikoerper, wu:fb73e10 antikoerper, wu:fi81c06 antikoerper, wu:fk25h01 antikoerper, beta-catenin antikoerper, ctnnb1 antikoerper, CHBCAT antikoerper, catenin (cadherin associated protein), beta 1 antikoerper, catenin beta 1 antikoerper, catenin (cadherin-associated protein), beta 1 antikoerper, catenin beta 1 L homeolog antikoerper, Ctnnb1 antikoerper, CTNNB1 antikoerper, ctnnb1 antikoerper, ctnnb1.L antikoerper
- Hintergrund
- Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
- Molekulargewicht
- 92 kDa
- UniProt
- P35222
- Pathways
- Peptide Hormone Metabolism
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