NFKBIB Antikörper

Produktnummer ABIN7250443

Produktdetails anti-NFKBIB Antikörper

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NFKBIB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Protein A purification

Immunogen: Recombinant Protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:200, IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NFKBIB

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Andere Bezeichnung: NFKBIB (NFKBIB Produkte)

Synonyme: NFKBIB antikoerper, IKB-beta antikoerper, IKappaBbeta antikoerper, IkB antikoerper, IkBb antikoerper, IKBB antikoerper, TRIP9 antikoerper, NFKB inhibitor beta antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antikoerper, NFKBIB antikoerper, Nfkbib antikoerper

Hintergrund: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

UniProt: Q15653

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades