PRKAA1/PRKAA2 Antikörper (pThr172, pThr183)
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- Target Alle PRKAA1/PRKAA2 Produkte
- PRKAA1/PRKAA2 (AMPK1/AMPK2)
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Bindungsspezifität
- pThr172, pThr183
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Reaktivität
- Human, Maus, Ratte, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRKAA1/PRKAA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthesized peptide derived from human AMPKalpha1/2 around the phosphorylation site of Thr183/172
- Isotyp
- IgG
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anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody
Reaktivität: Human, Maus, Ratte, Schwein, Schaf WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (Ser1071) antibodyReaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (Catalytic Domain), (N-Term) antibodyReaktivität: Human, Maus, Ratte, Drosophila melanogaster, Vertebrate WB, ELISA, IF, IHC (fro), IP Wirt: Maus Monoclonal 84-1 unconjugated
anti-AMPK1/AMPK2 (AA 14-47), (N-Term) antibodyReaktivität: Maus WB Wirt: Kaninchen Polyclonal RB43852 unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody (Cy7)Reaktivität: Human, Maus, Ratte, Schwein, Schaf WB, IF (cc), FACS, IF (p) Wirt: Kaninchen Polyclonal Cy7
anti-AMPK1/AMPK2 (Center) antibodyReaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (pSer172), (pSer183) antibodyReaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-AMPK1/AMPK2 (Ser1071) antibodyReaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PRKAA1/PRKAA2 (AMPK1/AMPK2)
- Andere Bezeichnung
- AMPK alpha1/2 (PRKAA1/PRKAA2 Produkte)
- Hintergrund
- AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
- Molekulargewicht
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Observed_MW: 63 kDa
Calculated_MW: 62 kDa
- UniProt
- Q13131, P54646
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