EEF2K Antikörper (pSer366)

Produktnummer ABIN7250797

Produktdetails anti-EEF2K Antikörper

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Bindungsspezifität: pSer366

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF2K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EEF2K

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Andere Bezeichnung: EEF2K (EEF2K Produkte)

Synonyme: HSU93850 antikoerper, eEF-2K antikoerper, C86191 antikoerper, SMEF2K antikoerper, eEF-2 kinase antikoerper, cb365 antikoerper, fa04b08 antikoerper, wu:fa04b08 antikoerper, zgc:100973 antikoerper, eukaryotic elongation factor 2 kinase antikoerper, eukaryotic elongation factor-2 kinase antikoerper, EEF2K antikoerper, Eef2k antikoerper, eef2k antikoerper, LOC101930123 antikoerper

Hintergrund: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Molekulargewicht:

Observed_MW: 105 kDa

Calculated_MW: 82 kDa

UniProt: O00418

Pathways: AMPK Signaling