ERK1/2 Antikörper (pTyr205, pTyr222)
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- Target Alle ERK1/2 (MAPK1/3) Antikörper anzeigen
- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
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Bindungsspezifität
- pTyr205, pTyr222
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ERK1/2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Protein A purification
- Immunogen
- Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205)
- Klon
- 4D4
- Isotyp
- IgG
- Top Product
- Discover our top product MAPK1/3 Primärantikörper
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- Applikationshinweise
- IHC 1:100-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
- Andere Bezeichnung
- ERK 1/2 (MAPK1/3 Produkte)
- Synonyme
- erk1/2 antikoerper, mitogen-activated protein kinase antikoerper, erk1/2 antikoerper
- Hintergrund
- Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
- UniProt
- P27361, P28482
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