Caspase 1 Antikörper (Cleaved-Asp210)
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- Target Alle Caspase 1 (CASP1) Antikörper anzeigen
- Caspase 1 (CASP1)
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Bindungsspezifität
- Cleaved-Asp210
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthesized peptide derived from the Internal region of human Caspase-1
- Isotyp
- IgG
- Top Product
- Discover our top product CASP1 Primärantikörper
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- Applikationshinweise
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Caspase 1 (CASP1)
- Andere Bezeichnung
- CASP1 (CASP1 Produkte)
- Hintergrund
- Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
- Molekulargewicht
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Observed_MW: 25 kDa
Calculated_MW: 45 kDa
- UniProt
- P29466
- Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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