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Caspase 1 Antikörper (Cleaved-Asp210)

Name: Caspase 1 Antikörper (Cleaved-Asp210)
Brand: antibodies-online
SKU: ABIN7251010
Price: 538.8 EUR
Availability: InStock

CASP1 Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated

Western Blot analysis of NIH-3T3 cells using Cleaved-CASP1 (D210) Polyclonal Antibody at dilution of 1:1000. (Caspase 1 Antikörper (Cleaved-Asp210))

Immunohistochemistry of paraffin-embedded Human breast cancer tissue using Cleaved-CASP1 (D210) Polyclonal Antibody at dilution of 1:200. (Caspase 1 Antikörper (Cleaved-Asp210))

IHC (p)

Immunofluorescence analysis of Human stomach cancer tissue using Cleaved-CASP1 (D210) Polyclonal Antibody at dilution of 1:200. (Caspase 1 Antikörper (Cleaved-Asp210))

3 Abbildungen

Produktnummer ABIN7251010

Datenblatt (PDF)

Target Alle Caspase 1 (CASP1) Antikörper anzeigen

Caspase 1 (CASP1)
Bindungsspezifität
10

8

7

7

5

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cleaved-Asp210
Reaktivität
97

36

29

5

2

2

1

1

1

1

1
Human
Wirt
108

10

4

1
Kaninchen
Passende Sekundärantikörper
Klonalität
100

23
Polyklonal
Konjugat
81

19

8

4

2

2

2

2

2

2
Dieser Caspase 1 Antikörper ist unkonjugiert
Applikation
95

51

47

20

14

13

12

5

4

3

3

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktmerkmale

Polyclonal Antibody

Aufreinigung

Affinity purification

Immunogen

Synthesized peptide derived from the Internal region of human Caspase-1

Isotyp

IgG

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Applikationshinweise

WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

Caspase 1 (CASP1)

Andere Bezeichnung

CASP1 (CASP1 Produkte)

Hintergrund

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Molekulargewicht

Observed_MW: 25 kDa
Calculated_MW: 45 kDa

UniProt

P29466

Pathways

Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome