Notch1 Antikörper (Cleaved-Val1754)
-
- Target Alle Notch1 (NOTCH1) Antikörper anzeigen
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
-
Bindungsspezifität
- Cleaved-Val1754
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Notch1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthesized peptide derived from the Internal region of human Notch 1
- Isotyp
- IgG
- Top Product
- Discover our top product NOTCH1 Primärantikörper
-
anti-Notch 1 (NOTCH1) antibody (PE)
NOTCH1 Reaktivität: Human, Maus FACS Wirt: Maus Monoclonal mN1A PE
anti-Notch 1 (NOTCH1) antibody (APC)NOTCH1 Reaktivität: Human, Maus FACS Wirt: Maus Monoclonal mN1A APC
anti-Notch 1 (NOTCH1) (AA 2101-2300) antibodyNOTCH1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Notch 1 (NOTCH1) (AA 20-216) antibodyNOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 unconjugated
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (HRP)NOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 HRP
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (FITC)NOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 FITC
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Biotin)NOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 Biotin
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (PE)NOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 PE
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (APC)NOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 APC
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (PerCP)NOTCH1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal S253-32 PerCP
-
- Applikationshinweise
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- Andere Bezeichnung
- NOTCH1 (NOTCH1 Produkte)
- Hintergrund
- This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.
- Molekulargewicht
-
Observed_MW: 110 kDa
Calculated_MW: 273 kDa
- UniProt
- P46531
- Pathways
- Notch Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
-
