SPACA3 Antikörper

Produktnummer ABIN7252069

Produktdetails anti-SPACA3 Antikörper

Target: SPACA3 (Sperm Acrosome Associated Protein 3 (SPACA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPACA3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPACA3

Target: SPACA3 (Sperm Acrosome Associated Protein 3 (SPACA3))

Andere Bezeichnung: SPACA3 (SPACA3 Produkte)

Synonyme: 1700025M08Rik antikoerper, ALLP17 antikoerper, CT54 antikoerper, LYC3 antikoerper, LYZL3 antikoerper, SLLP1 antikoerper, Lyc3 antikoerper, mSLLP1 antikoerper, SPRASA antikoerper, sperm acrosome associated 3 antikoerper, SPACA3 antikoerper, Spaca3 antikoerper

Hintergrund: SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms, SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.

UniProt: Q8IXA5

Pathways: Glycosaminoglycan Metabolic Process