EDARADD Antikörper

Produktnummer ABIN7252072

Produktdetails anti-EDARADD Antikörper

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDARADD Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:35-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EDARADD

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Andere Bezeichnung: EDARADD (EDARADD Produkte)

Synonyme: 1810032E07Rik antikoerper, 5830469M23Rik antikoerper, A630043P06 antikoerper, cr antikoerper, ECTD11A antikoerper, ECTD11B antikoerper, ED3 antikoerper, EDA3 antikoerper, EDAR (ectodysplasin-A receptor)-associated death domain antikoerper, EDAR associated death domain antikoerper, Edaradd antikoerper, EDARADD antikoerper

Hintergrund: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway