Spartan Antikörper

Produktnummer ABIN7252330

Produktdetails anti-Spartan Antikörper

Target: Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Spartan Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human SPRTN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Spartan

Target: Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))

Andere Bezeichnung: SPRTN (C1orf124 Produkte)

Synonyme: Spartan antikoerper, c1orf124 antikoerper, C1orf124 antikoerper, DDDL1880 antikoerper, DVC1 antikoerper, PRO4323 antikoerper, dJ876B10.3 antikoerper, C28H1orf124 antikoerper, SprT-like N-terminal domain antikoerper, sprtn antikoerper, SPRTN antikoerper

Hintergrund: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.

UniProt: Q9H040