MICU1 Antikörper

Produktnummer ABIN7252387

Produktdetails anti-MICU1 Antikörper

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MICU1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human MICU1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MICU1

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Andere Bezeichnung: MICU1 (MICU1 Produkte)

Synonyme: CALC antikoerper, CBARA1 antikoerper, EFHA3 antikoerper, C730016L05Rik antikoerper, Calc antikoerper, Cbara1 antikoerper, mitochondrial calcium uptake 1 antikoerper, MICU1 antikoerper, Micu1 antikoerper

Hintergrund: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

UniProt: Q9BPX6