Syntaxin 5 Antikörper

Produktnummer ABIN7252510

Produktdetails anti-Syntaxin 5 Antikörper

Target: Syntaxin 5 (STX5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human STX5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Syntaxin 5

Target: Syntaxin 5 (STX5)

Andere Bezeichnung: STX5 (STX5 Produkte)

Synonyme: BG:DS02740.12 antikoerper, CG4214 antikoerper, DmSyx5 antikoerper, Dmel\\CG4214 antikoerper, II antikoerper, SED5 antikoerper, SYN5 antikoerper, Sed5 antikoerper, Synx5 antikoerper, Syx antikoerper, Syx5A antikoerper, anon-35Fb antikoerper, anon-35Fd antikoerper, dSed5 antikoerper, dSed5p antikoerper, dSyx5 antikoerper, dsed5 antikoerper, l(2)35Ff antikoerper, sed5 antikoerper, syn5 antikoerper, syx5 antikoerper, zgc:91864 antikoerper, wu:fj81f08 antikoerper, stx5a antikoerper, Syntaxin-5 antikoerper, MGC114979 antikoerper, STX5A antikoerper, Stx5a antikoerper, 0610031F24Rik antikoerper, D19Ertd627e antikoerper, Stx5 antikoerper, Syntaxin 5 antikoerper, syntaxin 5A antikoerper, syntaxin 5 antikoerper, syntaxin 5 L homeolog antikoerper, syntaxin 5, putative antikoerper, Qa-SNARE protein antikoerper, Syx5 antikoerper, stx5a antikoerper, STX5 antikoerper, stx5 antikoerper, stx5.L antikoerper, TA12540 antikoerper, LMJF_32_0070 antikoerper, LOC732925 antikoerper, Stx5 antikoerper, Stx5a antikoerper

Hintergrund: The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa ("long") protein localized to the Golgi complex and endoplasmic reticulum, and a ""short"" 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 40 kDa

UniProt: Q13190

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size, Synaptic Vesicle Exocytosis