HLA-DPB1 Antikörper
-
- Target Alle HLA-DPB1 Antikörper anzeigen
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser HLA-DPB1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Fusion protein of human HLA-DPB1
- Isotyp
- IgG
- Top Product
- Discover our top product HLA-DPB1 Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- Andere Bezeichnung
- HLA-DPB1 (HLA-DPB1 Produkte)
- Synonyme
- PATR-DPB1 antikoerper, B-LB antikoerper, B-LB2 antikoerper, B-LB21 antikoerper, BLB1 antikoerper, GSP-BLB1 antikoerper, DPB1 antikoerper, HLA-DP antikoerper, HLA-DP1B antikoerper, HLA-DPB antikoerper, major histocompatibility complex, class II, DP beta 1 antikoerper, Major histocompatibility complex class II beta chain BLB1 antikoerper, PATR-DPB1 antikoerper, BLB1 antikoerper, HLA-DPB1 antikoerper
- Hintergrund
- HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
- Molekulargewicht
-
Observed_MW: Refer to figures
Calculated_MW: 29 kDa
- UniProt
- P04440
- Pathways
- T-Zell Rezeptor Signalweg, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
-