arl2bp antikoerper, MGC81575 antikoerper, MGC84796 antikoerper, MGC130948 antikoerper, MGC107872 antikoerper, ARL2BP antikoerper, BART antikoerper, BART1 antikoerper, 1700010P10Rik antikoerper, 1700027H16Rik antikoerper, 6330544B05Rik antikoerper, AI482273 antikoerper, AI849834 antikoerper, Bart1 antikoerper, zgc:66308 antikoerper, zgc:77496 antikoerper, ADP ribosylation factor like GTPase 2 binding protein L homeolog antikoerper, ADP ribosylation factor like GTPase 2 binding protein antikoerper, ADP-ribosylation factor-like 2 binding protein antikoerper, ADP-ribosylation factor like GTPase 2 binding protein antikoerper, arl2bp.L antikoerper, arl2bp antikoerper, ARL2BP antikoerper, Arl2bp antikoerper
Hintergrund
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.ARL2BP (ADP Ribosylation Factor Like GTPase 2 Binding Protein) is a Protein Coding gene. Diseases associated with ARL2BP include Retinitis Pigmentosa With Or Without Situs Inversus and Arl2bp-Related Retinitis Pigmentosa. Among its related pathways are Integration of energy metabolism and Metabolism. GO annotations related to this gene include transcription coactivator activity and GTPase regulator activity.