CNOT7 Antikörper

Produktnummer ABIN7253965

Produktdetails anti-CNOT7 Antikörper

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human CNOT7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Andere Bezeichnung: CNOT7 (CNOT7 Produkte)

Synonyme: CNOT7 antikoerper, CAF1 antikoerper, fd59c07 antikoerper, fj07d05 antikoerper, wu:fd59c07 antikoerper, wu:fj07d05 antikoerper, zgc:153168 antikoerper, caf1 antikoerper, Caf1a antikoerper, hCAF-1 antikoerper, AU022737 antikoerper, CAF-1 antikoerper, Caf1 antikoerper, Pop2 antikoerper, CCR4-NOT transcription complex subunit 7 antikoerper, ccr4-not transcription complex, subunit 7 antikoerper, CCR4-NOT transcription complex, subunit 7 antikoerper, ccr4-not transcription complex, subunit 7, putative antikoerper, CCR4-NOT transcription complex subunit 7 S homeolog antikoerper, CNOT7 antikoerper, CNL04550 antikoerper, GL50803_10606 antikoerper, GL50803_8209 antikoerper, CGB_D2510C antikoerper, cnot7 antikoerper, cnot7.S antikoerper, Cnot7 antikoerper

Hintergrund: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8.

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization