VGLL1 Antikörper

Produktnummer ABIN7254214

Produktdetails anti-VGLL1 Antikörper

Target: VGLL1 (Vestigial Like 1 (VGLL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VGLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human VGLL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:10000 ELISA 1:2000-1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu VGLL1

Target: VGLL1 (Vestigial Like 1 (VGLL1))

Andere Bezeichnung: VGLL1 (VGLL1 Produkte)

Synonyme: TDU antikoerper, VGL1 antikoerper, RGD1564038 antikoerper, VGLL1 antikoerper, vgl1 antikoerper, Tondu antikoerper, vestigial like family member 1 antikoerper, vestigial-like family member 1 antikoerper, VGLL1 antikoerper, Vgll1 antikoerper, vgll1 antikoerper

Hintergrund: The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 29 kDa

UniProt: Q99990