RAD54B antikoerper, im:7137737 antikoerper, im:7153525 antikoerper, fsbp antikoerper, rdh54 antikoerper, RDH54 antikoerper, E130016E03Rik antikoerper, Fsbp antikoerper, RGD1306507 antikoerper, RAD54 homolog B (S. cerevisiae) antikoerper, RAD54 homolog B L homeolog antikoerper, RAD54B antikoerper, rad54b antikoerper, rad54b.L antikoerper, Rad54b antikoerper
Hintergrund
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.