KRTAP11-1 Antikörper

Produktnummer ABIN7006990

Produktdetails anti-KRTAP11-1 Antikörper

Target: KRTAP11-1 (Keratin Associated Protein 11-1 (KRTAP11-1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRTAP11-1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human KRTAP11-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KRTAP11-1

Target: KRTAP11-1 (Keratin Associated Protein 11-1 (KRTAP11-1))

Andere Bezeichnung: KRTAP11-1 (KRTAP11-1 Produkte)

Hintergrund: Hair is a structure that is unique to mammals. It plays an important role in the retention of heat, as well as sexual dimorphism, attraction of mates and protection of skin. The major components of hair are -keratins and keratin-associated proteins (KRTAPs or KAPs), each of which are encoded by multigene families. Hair keratins form an intermediate filament (IF) network, which is embedded in an interfilamentous matrix consisting of KRTAPs. KRTAPS comprise three major groups, which are essential for the formation of rigid and resistant hair shafts through disulfide bond cross-linking or hydrophobic interactions with keratins. These groups are designated high cysteine (HS), which includes subfamilies 1, 2, 3, 10, 12, 16, 29 and 31, ultrahigh cysteine, including subfamilies 4, 5, 9, 17, 28, 30, 32 and 33, and high glycine-tyrosine (HGT), which includes subfamilies 6, 7, 8, 19, 20 and 21. In addition, subfamilies 11, 13, 24-27, 29, 34 and 35 have high serine content but relative low cysteine content. After further phylogenetic studies, subfamilies 14 and 15 have been grouped with subfamily 13 and subfamily 22 was combined with subfamily 19.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 17 kDa

UniProt: Q8IUC1