ARHGDIB Antikörper

Produktnummer ABIN7254544

Produktdetails anti-ARHGDIB Antikörper

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human ARHGDIB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Andere Bezeichnung: ARHGDIB (ARHGDIB Produkte)

Synonyme: ARHGDIB antikoerper, zgc:65966 antikoerper, arhgdib antikoerper, MGC69067 antikoerper, gdia2 antikoerper, rhodgi-2 antikoerper, rhodgi2 antikoerper, D4 antikoerper, GDIA2 antikoerper, GDID4 antikoerper, LYGDI antikoerper, Ly-GDI antikoerper, RAP1GN1 antikoerper, RhoGDI2 antikoerper, Gdid4 antikoerper, Rho GDP dissociation inhibitor (GDI) gamma antikoerper, Rho GDP dissociation inhibitor (GDI) beta S homeolog antikoerper, Rho GDP dissociation inhibitor beta antikoerper, Rho GDP dissociation inhibitor (GDI) beta antikoerper, Rho, GDP dissociation inhibitor (GDI) beta antikoerper, arhgdig antikoerper, arhgdib.S antikoerper, ARHGDIB antikoerper, arhgdib antikoerper, Arhgdib antikoerper

Hintergrund: ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them. It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: P52566

Pathways: Caspase Kaskade in der Apoptose