XAB2 Antikörper
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- Target Alle XAB2 Antikörper anzeigen
- XAB2 (XPA Binding Protein 2 (XAB2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser XAB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human XAB2
- Isotyp
- IgG
- Top Product
- Discover our top product XAB2 Primärantikörper
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anti-XPA Binding Protein 2 (XAB2) (AA 1-855) antibody
XAB2 Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 1D1-1A9 unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 750-840) antibodyXAB2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (N-Term) antibodyXAB2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyVerified XAB2 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) antibodyXAB2 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 450-479) antibodyXAB2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB20045 unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 35-84) antibodyXAB2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schwein, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyXAB2 Reaktivität: Human, Maus, Ratte, Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyXAB2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Drosophila melanogaster WB Wirt: Kaninchen Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (N-Term) antibodyXAB2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.4 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- XAB2 (XPA Binding Protein 2 (XAB2))
- Andere Bezeichnung
- XAB2 (XAB2 Produkte)
- Hintergrund
- HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and Cyclophilin E) and is required for proper RNA synthesis in the cell. In addition, HCNP functions as a component of the RAR corepressor complex with RAR and HDAC3 and exhibits an inhibitory effect on ATRA-induced cell differentiation. This suggests that HCNP may function as useful target in cancer therapy.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 100 kDa
- UniProt
- Q9HCS7
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