XRCC1 Antikörper

Produktnummer ABIN7254911

Produktdetails anti-XRCC1 Antikörper

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human XRCC1 (NP_006288.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu XRCC1

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Andere Bezeichnung: XRCC1 (XRCC1 Produkte)

Synonyme: xrcc1 antikoerper, MGC80909 antikoerper, XRCC1 antikoerper, rcc antikoerper, RCC antikoerper, Xrcc-1 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 1 antikoerper, X-ray repair cross complementing 1 antikoerper, xrcc1 antikoerper, XRCC1 antikoerper, Xrcc1 antikoerper

Hintergrund: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Gen-ID: 7515

UniProt: P18887

Pathways: DNA Reparatur