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SFPQ Antikörper

SFPQ Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7255047
  • Target Alle SFPQ Antikörper anzeigen
    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
    Reaktivität
    • 47
    • 21
    • 17
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 45
    • 2
    Kaninchen
    Klonalität
    • 36
    • 11
    Polyklonal
    Konjugat
    • 26
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SFPQ Antikörper ist unkonjugiert
    Applikation
    • 34
    • 20
    • 13
    • 10
    • 9
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SFPQ (NP_005057.1).
    Isotyp
    IgG
    Top Product
    Discover our top product SFPQ Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
    Andere Bezeichnung
    SFPQ (SFPQ Produkte)
    Synonyme
    1110004P21Rik antikoerper, 2810416M14Rik antikoerper, 5730453G22Rik antikoerper, 9030402K04Rik antikoerper, AU021830 antikoerper, D4Ertd314e antikoerper, Gm12940 antikoerper, OTTMUSG00000009329 antikoerper, PSF antikoerper, REP1 antikoerper, hm:zeh0027 antikoerper, wu:fa11h12 antikoerper, wu:fd10f03 antikoerper, zgc:85935 antikoerper, POMP100 antikoerper, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) antikoerper, splicing factor proline/glutamine-rich antikoerper, splicing factor proline and glutamine rich antikoerper, Sfpq antikoerper, sfpq antikoerper, SFPQ antikoerper
    Hintergrund
    DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45, a phosphorylated form is sequestered by THRAP3 from the pre-mRNA in resting T-cells, T-cell activation and subsequent reduced phosphorylation is proposed to lead to release from THRAP3 allowing binding to pre-mRNA splicing regulatotry elements which represses exon inclusion. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A.
    Molekulargewicht

    Observed_MW: 115 kDa

    Calculated_MW: 72 kDa/76 kDa

    Gen-ID
    6421
    UniProt
    P23246
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