PTPRJ Antikörper
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- Target Alle PTPRJ Antikörper anzeigen
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PTPRJ Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PTPRJ (NP_002834.3).
- Isotyp
- IgG
- Top Product
- Discover our top product PTPRJ Primärantikörper
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- Applikationshinweise
- WB 1:200-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- Andere Bezeichnung
- PTPRJ (PTPRJ Produkte)
- Synonyme
- HAAP antikoerper, CD148 antikoerper, DEP1 antikoerper, HPTPeta antikoerper, R-PTP-ETA antikoerper, SCC1 antikoerper, AI450271 antikoerper, BET antikoerper, Byp antikoerper, DEP-1 antikoerper, PTPbeta2 antikoerper, Ptpb2 antikoerper, RPTPJ antikoerper, Scc-1 antikoerper, Scc1 antikoerper, PTPRJ antikoerper, acid phosphatase 1 antikoerper, protein tyrosine phosphatase, receptor type J antikoerper, protein tyrosine phosphatase, receptor type, J antikoerper, ACP1 antikoerper, PTPRJ antikoerper, Ptprj antikoerper, EUBREC_2762 antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 260 kDa
Calculated_MW: 57 kDa/145 kDa
- Gen-ID
- 5795
- UniProt
- Q12913
- Pathways
- EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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