SIGLEC8 Antikörper

Produktnummer ABIN7255347

Produktdetails anti-SIGLEC8 Antikörper

Target: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIGLEC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SIGLEC8 (NP_055257.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SIGLEC8

Target: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Andere Bezeichnung: SIGLEC8 (SIGLEC8 Produkte)

Synonyme: SAF2 antikoerper, SIGLEC-8 antikoerper, SIGLEC8L antikoerper, SIGLEC8 antikoerper, sialic acid binding Ig like lectin 8 antikoerper, sialic acid-binding Ig-like lectin 8 antikoerper, SIGLEC8 antikoerper, LOC506364 antikoerper

Hintergrund: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein .

Molekulargewicht:

Observed_MW: 60 kDa

Calculated_MW: 44 kDa/46 kDa/54 kDa

Gen-ID: 27181

UniProt: Q9NYZ4