YWHAE Antikörper

Produktnummer ABIN7255377

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch YWHAE in IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für YWHAE Antikörper (ABIN7255377)

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YWHAE Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-YWHAE Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human YWHAE (NP_006752.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Andere Bezeichnung: YWHAE

Hintergrund: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Gen-ID: 7531

UniProt: P62258

Pathways: Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase