FAM3B Antikörper

Produktnummer ABIN7255421

Produktdetails anti-FAM3B Antikörper

Target: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM3B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human FAM3B (NP_478066.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200 IF 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FAM3B

Target: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Andere Bezeichnung: FAM3B (FAM3B Produkte)

Synonyme: 2-21 antikoerper, C21orf11 antikoerper, C21orf76 antikoerper, ORF9 antikoerper, PANDER antikoerper, 9030624C24Rik antikoerper, D16Jhu19e antikoerper, Pander antikoerper, RGD1311662 antikoerper, family with sequence similarity 3 member B antikoerper, family with sequence similarity 3, member B antikoerper, FAM3B antikoerper, Fam3b antikoerper

Substanzklasse: Viral Protein

Hintergrund: FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78 % sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5 % of the human genome.

Gen-ID: 54097

UniProt: P58499

Pathways: Hormone Transport