TCF4 Antikörper

Produktnummer ABIN7255616

Produktdetails anti-TCF4 Antikörper

Target: TCF4 (Transcription Factor 4 (TCF4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human TCF4 (NP_001077431.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Andere Bezeichnung: TCF4 (TCF4 Produkte)

Synonyme: E2-2 antikoerper, ITF-2 antikoerper, ITF2 antikoerper, PTHS antikoerper, SEF-2 antikoerper, SEF2 antikoerper, SEF2-1 antikoerper, SEF2-1A antikoerper, SEF2-1B antikoerper, TCF-4 antikoerper, bHLHb19 antikoerper, 5730422P05Rik antikoerper, ASP-I2 antikoerper, E2.2 antikoerper, ITF-2b antikoerper, ME2 antikoerper, MITF-2A antikoerper, MITF-2B antikoerper, TFE antikoerper, Tcf-4 antikoerper, TCF7L2 antikoerper, XE2 antikoerper, Xtcf-4 antikoerper, Xtcf4 antikoerper, e2-A antikoerper, tcf-4 antikoerper, transcription factor 4 antikoerper, transcription factor 4 S homeolog antikoerper, TCF4 antikoerper, Tcf4 antikoerper, tcf4 antikoerper, tcf4.S antikoerper

Hintergrund: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Molekulargewicht:

Observed_MW: 60 kDa

Calculated_MW: 48-71 kDa

Gen-ID: 6925

UniProt: P15884

Pathways: WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus