ACTN1 Antikörper
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- Target Alle ACTN1 Antikörper anzeigen
- ACTN1 (Actinin, alpha 1 (ACTN1))
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Reaktivität
- Human, Maus, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACTN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ACTN1 (NP_001123477.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ACTN1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ACTN1 (Actinin, alpha 1 (ACTN1))
- Andere Bezeichnung
- ACTN1 (ACTN1 Produkte)
- Synonyme
- ACTN1 antikoerper, actinin antikoerper, BDPLT15 antikoerper, 3110023F10Rik antikoerper, Actn1a antikoerper, actinin alpha 1 antikoerper, actinin, alpha 1 antikoerper, actinin alpha 1 L homeolog antikoerper, ACTN1 antikoerper, actn1 antikoerper, Actn1 antikoerper, actn1.L antikoerper
- Hintergrund
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 105 kDa
Calculated_MW: 102 kDa/103 kDa/105 kDa/107 kDa
- Gen-ID
- 87
- UniProt
- P12814
- Pathways
- Cell-Cell Junction Organization
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