MXI1 Antikörper

Produktnummer ABIN7255914

Produktdetails anti-MXI1 Antikörper

Target: MXI1 (MAX Interactor 1 (MXI1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MXI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human MXI1 (NP_569157.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Andere Bezeichnung: MXI1 (MXI1 Produkte)

Synonyme: mxi antikoerper, mad2 antikoerper, mxd2 antikoerper, xmxi1 antikoerper, MGC89544 antikoerper, MXI1 antikoerper, etID309773.22 antikoerper, fb16b12 antikoerper, fb55f03 antikoerper, wu:fb16b12 antikoerper, wu:fb55f03 antikoerper, wu:fd06a08 antikoerper, wu:fz74f10 antikoerper, ENSMUSG00000067085 antikoerper, Gm10197 antikoerper, Mad2 antikoerper, bHLHc11 antikoerper, MXI-WR antikoerper, MAD2 antikoerper, MXD2 antikoerper, MXI antikoerper, MAX interactor 1, dimerization protein antikoerper, max interactor 1, dimerization protein antikoerper, MAX interactor 1, dimerization protein L homeolog antikoerper, mxi1 antikoerper, MXI1 antikoerper, Mxi1 antikoerper, mxi1.L antikoerper

Hintergrund: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Molekulargewicht:

Observed_MW: 26 kDa

Calculated_MW: 20 kDa/21 kDa/26 kDa/32 kDa

Gen-ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location