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Hexosaminidase A Antikörper

HEXA Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7256120
  • Target Alle Hexosaminidase A (HEXA) Antikörper anzeigen
    Hexosaminidase A (HEXA)
    Reaktivität
    • 62
    • 24
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 52
    • 14
    Kaninchen
    Klonalität
    • 54
    • 12
    Polyklonal
    Konjugat
    • 40
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Hexosaminidase A Antikörper ist unkonjugiert
    Applikation
    • 54
    • 35
    • 13
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human HEXA (NP_000511.2).
    Isotyp
    IgG
    Top Product
    Discover our top product HEXA Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Hexosaminidase A (HEXA)
    Andere Bezeichnung
    HEXA (HEXA Produkte)
    Synonyme
    TSD antikoerper, fc04h11 antikoerper, wu:fc04h11 antikoerper, wu:fv09f06 antikoerper, si:dkey-35i22.2 antikoerper, HEXA antikoerper, Hex-1 antikoerper, zgc:112084 antikoerper, hexosaminidase subunit alpha antikoerper, hexosaminidase B (beta polypeptide) antikoerper, CUGBP Elav-like family member 6 antikoerper, hexosaminidase A antikoerper, hexosaminidase A (alpha polypeptide) antikoerper, beta-hexosaminidase subunit alpha-like antikoerper, HEXA antikoerper, hexb antikoerper, CELF6 antikoerper, Hexa antikoerper, hexa antikoerper, LOC100228061 antikoerper
    Hintergrund
    This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
    Gen-ID
    3073
    UniProt
    P06865
    Pathways
    Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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