PDIA2 antikoerper, DKFZp468D2220 antikoerper, 1810041F13Rik antikoerper, AI661267 antikoerper, Pdip antikoerper, Pdipl antikoerper, PDA2 antikoerper, PDI antikoerper, PDIP antikoerper, PDIR antikoerper, protein disulfide isomerase family A member 2 antikoerper, protein disulfide isomerase associated 2 antikoerper, protein disulfide isomerase family A, member 2 antikoerper, PDIA2 antikoerper, Pdia2 antikoerper
Hintergrund
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity.