DNAJB4 Antikörper

Produktnummer ABIN7256592

Produktdetails anti-DNAJB4 Antikörper

Target: DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DNAJB4 (NP_008965.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DNAJB4

Target: DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))

Andere Bezeichnung: DNAJB4 (DNAJB4 Produkte)

Synonyme: DNAJW antikoerper, DjB4 antikoerper, HLJ1 antikoerper, 1700029A20Rik antikoerper, 2010306G19Rik antikoerper, 5730460G06Rik antikoerper, zgc:91922 antikoerper, dnajb4 antikoerper, MGC83507 antikoerper, DNAJB4 antikoerper, DKFZp469B0618 antikoerper, DnaJ heat shock protein family (Hsp40) member B4 antikoerper, DnaJ (Hsp40) homolog, subfamily B, member 4 antikoerper, DnaJ heat shock protein family (Hsp40) member B4 S homeolog antikoerper, DnaJ homolog subfamily B member 4 antikoerper, putative dnaj homolog subfamily B member 4 antikoerper, DNAJB4 antikoerper, Dnajb4 antikoerper, dnajb4 antikoerper, dnajb4.S antikoerper, Bm1_16640 antikoerper, Smp_020920.1 antikoerper

Hintergrund: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 38 kDa

Calculated_MW: 37 kDa

Gen-ID: 11080

UniProt: Q9UDY4