desert Hedgehog Antikörper

Produktnummer ABIN7256690

Produktdetails anti-desert Hedgehog Antikörper

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser desert Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DHH (NP_066382.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Andere Bezeichnung: DHH (DHH Produkte)

Synonyme: GDXYM antikoerper, HHG-3 antikoerper, SRXY7 antikoerper, C78960 antikoerper, Xchh antikoerper, chh antikoerper, chh-a antikoerper, dhh antikoerper, dhh-1 antikoerper, dhh-A antikoerper, hh4 antikoerper, x-chh antikoerper, desert hedgehog antikoerper, desert hedgehog L homeolog antikoerper, desert hedgehog S homeolog antikoerper, DHH antikoerper, dhh antikoerper, Dhh antikoerper, dhh.L antikoerper, dhh.S antikoerper

Substanzklasse: Species

Hintergrund: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Molekulargewicht:

Observed_MW: 44 kDa

Calculated_MW: 43 kDa

Gen-ID: 50846

UniProt: O43323

Pathways: Hedgehog Signalweg