SSX2 Antikörper

Produktnummer ABIN7008339

Produktdetails anti-SSX2 Antikörper

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSX2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SSX2 (NP_783629.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SSX2

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Andere Bezeichnung: SSX2 (SSX2 Produkte)

Synonyme: CT5.2 antikoerper, CT5.2A antikoerper, HD21 antikoerper, HOM-MEL-40 antikoerper, SSX antikoerper, SSX2 antikoerper, SSX3 antikoerper, SSX family member 2 antikoerper, protein SSX2 antikoerper, synovial sarcoma, X breakpoint 2 antikoerper, SSX2 antikoerper, LOC741661 antikoerper, Ssx2 antikoerper

Hintergrund: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Gen-ID: 6757

UniProt: Q16385