CAMLG Antikörper
-
- Target Alle CAMLG Antikörper anzeigen
- CAMLG (Calcium Modulating Ligand (CAMLG))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CAMLG Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CAMLG (NP_001736.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CAMLG Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- CAMLG (Calcium Modulating Ligand (CAMLG))
- Andere Bezeichnung
- CAMLG (CAMLG Produkte)
- Synonyme
- MGC53900 antikoerper, CAML antikoerper, AI385748 antikoerper, Camlg antikoerper, Caml antikoerper, calcium modulating ligand L homeolog antikoerper, calcium modulating ligand antikoerper, camlg.L antikoerper, CAMLG antikoerper, camlg antikoerper, Caml antikoerper, Camlg antikoerper
- Hintergrund
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
- Molekulargewicht
-
Observed_MW: 38 kDa
Calculated_MW: 32 kDa
- Gen-ID
- 819
- UniProt
- P49069
- Pathways
- EGFR Signaling Pathway
-