GNB3 Antikörper
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- Target Alle GNB3 Antikörper anzeigen
- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GNB3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human GNB3 (NP_002066.1).
- Isotyp
- IgG
- Top Product
- Discover our top product GNB3 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
- Andere Bezeichnung
- GNB3 (GNB3 Produkte)
- Synonyme
- Gnb-3 antikoerper, MGC68913 antikoerper, MGC130764 antikoerper, gnb3 antikoerper, zgc:73058 antikoerper, zgc:77780 antikoerper, wu:fk54b04 antikoerper, gnb3l antikoerper, zgc:92641 antikoerper, G protein subunit beta 3 antikoerper, guanine nucleotide binding protein (G protein), beta 3 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3b antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3a antikoerper, GNB3 antikoerper, Gnb3 antikoerper, gnb3.S antikoerper, gnb3b antikoerper, gnb3a antikoerper
- Hintergrund
- Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
- Molekulargewicht
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Observed_MW: 37 kDa
Calculated_MW: 32 kDa/37 kDa
- Gen-ID
- 2784
- UniProt
- P16520
- Pathways
- Peptide Hormone Metabolism, Myometrial Relaxation and Contraction
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