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Endothelin 3 Antikörper

EDN3 Reaktivität: Maus IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7257539
  • Target Alle Endothelin 3 (EDN3) Antikörper anzeigen
    Endothelin 3 (EDN3)
    Reaktivität
    • 38
    • 4
    • 4
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 36
    • 3
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Endothelin 3 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 18
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human EDN3 (NP_996917.1).
    Isotyp
    IgG
    Top Product
    Discover our top product EDN3 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Endothelin 3 (EDN3)
    Andere Bezeichnung
    EDN3 (EDN3 Produkte)
    Synonyme
    et-3 antikoerper, EDN3 antikoerper, ET-3 antikoerper, ET3 antikoerper, HSCR4 antikoerper, PPET3 antikoerper, WS4B antikoerper, 114CH19 antikoerper, ls antikoerper, tmgc48 antikoerper, Et3 antikoerper, RGD1564825 antikoerper, preproET-3 antikoerper, endothelin-3 L homeolog antikoerper, endothelin 3 antikoerper, edn3.L antikoerper, EDN3 antikoerper, Edn3 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Gen-ID
    1908
    UniProt
    P14138
    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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