Endothelin 3 Antikörper

Produktnummer ABIN7257539

Produktdetails anti-Endothelin 3 Antikörper

Target: Endothelin 3 (EDN3)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human EDN3 (NP_996917.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Endothelin 3

Target: Endothelin 3 (EDN3)

Andere Bezeichnung: EDN3 (EDN3 Produkte)

Synonyme: et-3 antikoerper, EDN3 antikoerper, ET-3 antikoerper, ET3 antikoerper, HSCR4 antikoerper, PPET3 antikoerper, WS4B antikoerper, 114CH19 antikoerper, ls antikoerper, tmgc48 antikoerper, Et3 antikoerper, RGD1564825 antikoerper, preproET-3 antikoerper, endothelin-3 L homeolog antikoerper, endothelin 3 antikoerper, edn3.L antikoerper, EDN3 antikoerper, Edn3 antikoerper

Hintergrund: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gen-ID: 1908

UniProt: P14138

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones