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PNP Antikörper

NP Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7257591
  • Target Alle PNP (NP) Antikörper anzeigen
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Reaktivität
    • 36
    • 11
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 38
    • 4
    • 1
    • 1
    Kaninchen
    Klonalität
    • 41
    • 3
    Polyklonal
    Konjugat
    • 25
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PNP Antikörper ist unkonjugiert
    Applikation
    • 25
    • 17
    • 12
    • 9
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PNP (NP_000261.2).
    Isotyp
    IgG
    Top Product
    Discover our top product NP Primärantikörper
  • Applikationshinweise
    IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Andere Bezeichnung
    PNP (NP Produkte)
    Synonyme
    NP antikoerper, PRO1837 antikoerper, PUNP antikoerper, Np antikoerper, AL024301 antikoerper, AU015798 antikoerper, Np-1 antikoerper, Np-2 antikoerper, Pnp1 antikoerper, purine nucleoside phosphorylase antikoerper, purine-nucleoside phosphorylase antikoerper, PNP antikoerper, Pnp antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.
    Gen-ID
    4860
    UniProt
    P00491
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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