IQGAP3 Antikörper

Produktnummer ABIN7257710

Produktdetails anti-IQGAP3 Antikörper

Target: IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQGAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human IQGAP3 (NP_839943.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IQGAP3

Target: IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))

Andere Bezeichnung: IQGAP3 (IQGAP3 Produkte)

Synonyme: IQGAP3 antikoerper, AI593484 antikoerper, D030034H08 antikoerper, IQ motif containing GTPase activating protein 3 antikoerper, IQGAP3 antikoerper, iqgap3 antikoerper, Iqgap3 antikoerper

Hintergrund: IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Molekulargewicht:

Observed_MW: 170 kDa

Calculated_MW: 184 kDa

Gen-ID: 128239

UniProt: Q86VI3