HB58 antikoerper, Hbeta58 antikoerper, PEP8A antikoerper, VPS26 antikoerper, AA407240 antikoerper, Vps26 antikoerper, VPS26A antikoerper, MNC6.7 antikoerper, MNC6_7 antikoerper, vacuolar protein sorting 26A antikoerper, DKFZp459G2011 antikoerper, hb58 antikoerper, hbeta58 antikoerper, pep8a antikoerper, vps26 antikoerper, vps26a antikoerper, wu:fc67e06 antikoerper, zgc:56673 antikoerper, VPS26, retromer complex component A antikoerper, VPS26 retromer complex component A antikoerper, vacuolar protein sorting 26A antikoerper, vacuolar protein sorting 26 antikoerper, vacuolar protein sorting homolog26 antikoerper, vacuolar protein sorting 26 homolog A (S. pombe) pseudogene antikoerper, VPS26 retromer complex component A S homeolog antikoerper, VPS26 retromer complex component A L homeolog antikoerper, vacuolar protein sorting 26 homolog A (S. pombe) antikoerper, VPS26A antikoerper, Vps26a antikoerper, LOC692917 antikoerper, vpsh26 antikoerper, LOC100147400 antikoerper, vps26a.S antikoerper, vps26a.L antikoerper, vps26a antikoerper
Hintergrund
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.