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CAND1 Antikörper

CAND1 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7257782
  • Target Alle CAND1 Antikörper anzeigen
    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
    Reaktivität
    • 20
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 15
    • 5
    Kaninchen
    Klonalität
    • 16
    • 4
    Polyklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    Dieser CAND1 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 10
    • 5
    • 5
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CAND1 (NP_060918.2).
    Isotyp
    IgG
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  • Applikationshinweise
    IHC 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
    Andere Bezeichnung
    CAND1 (CAND1 Produkte)
    Hintergrund
    This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.
    Gen-ID
    55832
    UniProt
    Q86VP6
    Pathways
    Regulation of Actin Filament Polymerization
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