CAND1 Antikörper
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- Target Alle CAND1 Antikörper anzeigen
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CAND1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CAND1 (NP_060918.2).
- Isotyp
- IgG
- Top Product
- Discover our top product CAND1 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- Andere Bezeichnung
- CAND1 (CAND1 Produkte)
- Hintergrund
- This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.
- Gen-ID
- 55832
- UniProt
- Q86VP6
- Pathways
- Regulation of Actin Filament Polymerization
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