CAND1 Antikörper

Produktnummer ABIN7257782

Produktdetails anti-CAND1 Antikörper

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAND1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CAND1 (NP_060918.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CAND1

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Andere Bezeichnung: CAND1 (CAND1 Produkte)

Synonyme: TIP120 antikoerper, TIP120A antikoerper, ATCAND1 antikoerper, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 antikoerper, ETA2 antikoerper, HEMIVENATA antikoerper, HVE antikoerper, T8K22.14 antikoerper, T8K22_14 antikoerper, cullin-associated and neddylation dissociated antikoerper, Tip120 antikoerper, Tip120A antikoerper, fb78a05 antikoerper, wu:fb78a05 antikoerper, zgc:55729 antikoerper, tip120 antikoerper, tip120a antikoerper, cand2 antikoerper, 2310038O07Rik antikoerper, 6330512O03Rik antikoerper, AI195005 antikoerper, AI846556 antikoerper, D10Ertd516e antikoerper, Tp120a antikoerper, mKIAA0829 antikoerper, cullin associated and neddylation dissociated 1 antikoerper, cullin-associated and neddylation dissociated antikoerper, cullin-associated and neddylation-dissociated 1 antikoerper, cullin-associated and neddylation-dissociated 1 L homeolog antikoerper, cullin-associated NEDD8-dissociated protein 1 antikoerper, cullin associated and neddylation disassociated 1 antikoerper, CAND1 antikoerper, Cand1 antikoerper, cand1 antikoerper, cand1.L antikoerper, LOC100159824 antikoerper, LOC100177977 antikoerper

Hintergrund: This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.

Gen-ID: 55832

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization