Coagulation Factor X Antikörper

Produktnummer ABIN7257922

Produktdetails anti-Coagulation Factor X Antikörper

Target: Coagulation Factor X (F10)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor X Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human F10 (NP_000495.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Coagulation Factor X

Target: Coagulation Factor X (F10)

Andere Bezeichnung: F10 (F10 Produkte)

Synonyme: FX antikoerper, FXA antikoerper, Cf10 antikoerper, fX antikoerper, fi12c10 antikoerper, wu:fi12c10 antikoerper, F10 antikoerper, f10 antikoerper, coagulation factor X antikoerper, Coagulation factor X antikoerper, coagulation factor 10 L homeolog antikoerper, F10 antikoerper, f10 antikoerper, CpipJ_CPIJ012712 antikoerper, CpipJ_CPIJ014863 antikoerper, CpipJ_CPIJ016937 antikoerper, CpipJ_CPIJ017791 antikoerper, fa10 antikoerper, f10.L antikoerper

Hintergrund: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

Gen-ID: 2159

UniProt: P00742