LZTS2 Antikörper

Produktnummer ABIN7257980

Produktdetails anti-LZTS2 Antikörper

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LZTS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human LZTS2 (NP_115805.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LZTS2

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Andere Bezeichnung: LZTS2 (LZTS2 Produkte)

Synonyme: lapser1 antikoerper, MGC89253 antikoerper, si:dkey-250a11.1 antikoerper, LAPSER1 antikoerper, BC014695 antikoerper, mKIAA1813 antikoerper, Lapser1 antikoerper, leucine zipper, putative tumor suppressor 2 antikoerper, leucine zipper tumor suppressor 2 antikoerper, leucine zipper, putative tumor suppressor 2a antikoerper, leucine zipper, putative tumor suppressor 2 S homeolog antikoerper, lzts2 antikoerper, LZTS2 antikoerper, lzts2a antikoerper, Lzts2 antikoerper, lzts2.S antikoerper

Hintergrund: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 73 kDa

Calculated_MW: 72 kDa

Gen-ID: 84445

UniProt: Q9BRK4