UNC13B Antikörper
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- Target Alle UNC13B Antikörper anzeigen
- UNC13B (Unc-13 Homolog B (UNC13B))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UNC13B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human UNC13B (NP_006368.3).
- Isotyp
- IgG
- Top Product
- Discover our top product UNC13B Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- UNC13B (Unc-13 Homolog B (UNC13B))
- Andere Bezeichnung
- UNC13B (UNC13B Produkte)
- Synonyme
- MUNC13 antikoerper, UNC13 antikoerper, Unc13h2 antikoerper, UNC13B antikoerper, Munc13-2 antikoerper, Munc13-1 antikoerper, Unc13a antikoerper, Unc13h1 antikoerper, unc-13 homolog B antikoerper, unc-13 homolog B (C. elegans) antikoerper, UNC13B antikoerper, Unc13b antikoerper
- Hintergrund
- This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
- Molekulargewicht
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Observed_MW: 210 kDa
Calculated_MW: 180 kDa/182 kDa
- Gen-ID
- 10497
- UniProt
- O14795
- Pathways
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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