DDP2 antikoerper, TIM8B antikoerper, Ddp2 antikoerper, Tim8b antikoerper, translocase of inner mitochondrial membrane 8 homolog B antikoerper, translocase of inner mitochondrial membrane 8B antikoerper, TIMM8B antikoerper, Timm8b antikoerper
Hintergrund
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.