MAP3K3 Antikörper
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- Target Alle MAP3K3 Antikörper anzeigen
- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAP3K3 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MAP3K3 (NP_976226.1).
- Isotyp
- IgG
- Top Product
- Discover our top product MAP3K3 Primärantikörper
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-220) antibody
MAP3K3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 11-25), (N-Term) antibodyMAP3K3 Reaktivität: Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-90) antibodyMAP3K3 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (N-Term) antibodyMAP3K3 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 27-135) antibodyMAP3K3 Reaktivität: Human, Maus, Ratte, Hund WB, IF Wirt: Maus Monoclonal 40-MEKK3 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Center) antibodyMAP3K3 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Internal Region) antibodyMAP3K3 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Internal Region) antibodyMAP3K3 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (N-Term) antibodyMAP3K3 Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Affe, Drosophila melanogaster, Meerschweinchen, Hamster, Schwein, Schaf, Xenopus laevis WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) antibodyMAP3K3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC 1:100-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
- Andere Bezeichnung
- MAP3K3 (MAP3K3 Produkte)
- Synonyme
- MAPKKK3 antikoerper, MEKK3 antikoerper, AW548911 antikoerper, Mekk3 antikoerper, mKIAA4031 antikoerper, mitogen activated protein kinase kinase kinase 3 antikoerper, mitogen-activated protein kinase kinase kinase 3 antikoerper, Map3k3 antikoerper, MAP3K3 antikoerper, map3k3 antikoerper
- Hintergrund
- This gene product is a 626-amino acid polypeptide that is 96.5 % identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively, it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Gen-ID
- 4215
- UniProt
- Q99759
- Pathways
- MAPK Signalweg
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