IFI35 Antikörper
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- Target Alle IFI35 Antikörper anzeigen
- IFI35 (Interferon-Induced Protein 35 (IFI35))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFI35 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human IFI35 (NP_005524.2).
- Isotyp
- IgG
- Top Product
- Discover our top product IFI35 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IFI35 (Interferon-Induced Protein 35 (IFI35))
- Andere Bezeichnung
- IFI35 (IFI35 Produkte)
- Synonyme
- IFI35 antikoerper, IFP35 antikoerper, 2010008K16Rik antikoerper, AW986054 antikoerper, ifi-35 antikoerper, interferon induced protein 35 antikoerper, interferon-induced protein 35 antikoerper, IFI35 antikoerper, ifi35 antikoerper, Ifi35 antikoerper
- Hintergrund
- The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.
- Molekulargewicht
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Observed_MW: 35 kDa
Calculated_MW: 31 kDa
- Gen-ID
- 3430
- UniProt
- P80217
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